Quantitative 3-tesla multiparametric MRI in differentiation between renal cell carcinoma subtypes

Abstract Background MRI provides several distinct quantitative parameters that may better differentiate renal cell carcinoma (RCC) subtypes. The purpose of the study is to evaluate diagnostic accuracy apparent diffusion coefficient (ADC), chemical shift signal intensity index (SII), and contrast enhancement in differentiation between different subtypes carcinoma. Results There were 63 RCC as regard surgical histopathological analysis: 43 clear (ccRCC), 12 papillary (pRCC), 8 chromophobe (cbRCC). mean ADC ratio for ccRCC (0.75 ± 0.13) was significantly higher than pRCC (0.46 0.12, P < 0.001) cbRCC (0.41 0.15, 0.001). value (1.56 0.27 × 10 −3 mm 2 /s) (0.96 0.25 /s, (0.89 0.29 SII (1.49 0.04) (0.93 0.01, (1.01 0.16, absolute corticomedullary (196.7 81.6) greater (177.8 77.7, (164.3 84.6, Conclusion Our demonstrated multiparametric able afford some features such ratio, SII, which can be used accurately distinguish